Chris Tillman, who won his 15th game last Thursday, will have to try again for his 16th.
Tillman walked five in 5 1/3 innings, allowing four runs on five hits. He struck out three. It was the most walks he allowed since Sept. 19, 2010.
His ineffectiveness was key in the Orioles’ 4-3 loss to the Cleveland Indians at Progressive Field.
The Orioles are 3-5 on their vital road trip to Boston, New York and Cleveland. The trip ends with a game against the Indians on Wednesday night.
In the fourth, Jason Kipnis and Carlos Santana started the inning by walking off Tillman. Mickey Brantley bunted both runners up a base, and Kipnis scored on a sacrifice fly by Asdrubal Cabrera.
Tillman (15-5) was knocked out in the sixth. Santana walked, Brantley doubled him to third. Santana scored on Cabrera’s second sacrifice fly. Jason Kubel was walked intentionally, and Yan Gomes doubled to score Brantley and Matt Carson, who ran for Kubel. Cleveland (73-65) led 4-0.
The Orioles’ first real chance to score off Ubaldo Jimenez came in the second when Adam Jones and Michael Morse singled, but with first and third with none out, Nick Markakis fouled out and J.J. Hardy flied out.
Baltimore (73-64) later loaded the bases on a single by Manny Machado and walks to Chris Davis and Matt Wieters. Morse bounced out to Jimenez, ending the inning.
Jimenez (10-9) threw six scoreless innings, allowing four hits, walking two and striking out four.
Cody Allen pitched a scoreless seventh. Joe Smith worked the eighth.
In the ninth, Markakis and Hardy started the inning with singles off Chris Perez. Nate McLouth homered to right, his 11th of the year, and the Orioles trailed by 4-3.
Perez struck out Brian Roberts and Machado. Davis grounded to second to end the game.